Endocrine Abstracts

Background: Hypoparathyroidism (HypoPT) is a rare condition that is characterized by hypocalcemia and hyperphosphatemia due to low or inappropriately normal serum levels of parathyroid hormone (PTH) for at least 6 months. The long-term complications of hypoparathyroidism indicate the necessity of screening them. In the follow-up of these patients according to hypoparathyroidism guidelines is recommended; calcium, phosphorus, albumin, magnesium, creatinine, and eGFR levels shou...

Introduction: Insulinoma is a rare neuroendocrine tumor that is difficult to diagnose due to its obscure location. Conventional radiographic methods have low sensitivity and are inadequate to detect insulinoma. Selective arterial calcium stimulation test (SACST) is 95–100% sensitive in the diagnosis of insulinomas. Here, we presented two cases of insulinoma that could not be located by radiographic methods and evaluated them with SACST.Case 1: A 48-...

Introduction: While Graves’ disease is a common cause of thyrotoxicosis, tyroid hormone resistance (THR) is a rare cause of high thyroid hormones. Coexistence of Graves’ disease and THR which can cause quite a lot of difficulties in diagnosis and treatment was reported very rarely in the literature. Here, we report a patient with THR and Graves’ disease in whom remission was achieved with medical therapy.Case: A 38-year-old woman applied t...

Aim: To determine whether early repeat fine needle aspiration biopsy(FNAB) has an effect on adequate or atypia of undetermined significance/follicular lesion of undetermined significance(AUS/FLUS) cytology rates in thyroid nodules with inadequate or AUS/FLUS in the first FNAB.Method: Nodules of patients who underwent repeat biopsy due to insufficient or AUS/FLUS cytology between 2019-2022 were included. Demographic data of the patients and ultrasonograph...

Introduction: Immune checkpoint inhibitors are relatively new and promising treatments for a variety of solid tumors. Nivolumab is an anti-cancer monoclonal antibody that inhibits anti-programmed death-1 (PD1) and modulates T-cell response. It has been shown to significantly improve survival in many types of cancer, but clinical studies have also reported an increased risk of developing immune-related adverse events. In particular, immune-related adverse events may be related ...

Von Hippel-Lindau (VHL) syndrome is a pathological condition that causes various clinical symptoms and is difficult to diagnose. The most common pathological lesions are hemangioblastomas of the central nervous system, retinal angiomas, renal clear cell carcinomas, and pheochromocytomas. Here we reposrt a case of likely to be VHL due to his family history.Case: A 33-year-old male suffering from hypertension and a history of hemangioblastoma operated in 2...

Background: Primary Hyperparathyroidism (PHPT) is a common endocrine disorder that is characterized by hypercalcaemia and elevated or inappropriately normal serum levels of parathyroid hormone. Most often, the presentation of PHPT is asymptomatic. PHPT can manifest with osteoporosis and hypercalciuria as well as with vertebral fractures and nephrolithiasis, both of which can be asymptomatic. Our aim in this study; to determine the frequency of kidney stones in patients operate...

Background: Micro vascular complications are the major outcome of Type 2 Diabetes Mellitus progression, which reduces the quality of life and increases diabetic morbidity & mortality. As the incidence of type 2 diabetes is growing day by day; our search for its aetiology and pathogenesis is also ever growing to predict its risk factors and early screening for better care and prevention of its complications. Many studies have tried to link susceptibility of type 2 diabetes ...

Aim: Although thyroid nodules located in isthmus were less frequent, papillary thyroid cancer in this location was reported to be more aggressive in some studies. Our aim was to evaluate hormonal, ultrasonographic, and cytopathologic features of nodules located in isthmus (isthmic nodules).Material and methods: Data of patients who underwent thyroidectomy between 2006–2014 were reviewed retrospectively. Hormonal, ultrasonographic, and cytopathologic...

Aim: It has been reported that thyrotrophin receptor antibody (TRAb) is associated with frequency and aggressiveness of thyroid cancer in patients with Graves disease (GD). However, there is not any data regarding the effects of TRAb on cytology and histopathology results of patients with nodular GD. Thus, the aim of the present study is to evaluate the effects of TRAb on cytology and histopathology results in patients with nodular or multinodular thyroid disease on the basis ...